Laboratory of Cancer Biology

Cancer Biology

Last modified: 26.06.2014

“The laboratory for cancer biology are trying to advance our understanding into the mechanisms underpinning brain tumor pathology with the hope to find new cancer stem cell markers for therapeutic targeting of this life threatening disease.
Identifying disease footprints “Biomarkers” for targeted therapy in Glioblastoma tissue and blood is just one milestone in our research. Working closely with groups within Biomedicine and the Neurosurgery and Oncology Department at Aalborg University Hospital, we are characterizing our biomarker candidates to facilitate our step forward on the road of discovery and clinical application.”

Specific Research projects:

  • Identifying tumour biomarkers and mi RNA signatures in glioblastoma
  • Characterisation of novel Cancer stem cell marker (Cripto-1) in GBM and targeted therapy
  • Cripto-1 as a prognostic marker in plasma for tumor progression
  • miRNA in Glioblastoma: MicroRNA Signatures of Progression Free survival in GBM patients
  • Glioblastoma infiltration and migration: the regulation and functional role of Brain Fatty Acid Binding Protein 7 (FABP7).
  • Expression profiling in GBM tissue: Primary resection versus relapse. Looking at tumor subtypes and individual patient profiles with time
  • Exosomes as targeted delivery vehicles in the treatment of GBM: the use of adipose-derived Stem Cells as targeted therapy
  • MiRNA signatures of Migraine and Pain
  • Molecular mechanisms underpinning chemotherapy induced pain
     

 

publications

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Contact information

Head of Laboratory
Meg Duroux, Associate professor, PhD
Laboratory of Cancer Biology
Dept. of Health Science and Technology
Aalborg University
Fredrik Bajers Vej 3B
DK-9220 Aalborg
Denmark
E-mail: megd@hst.aau.dk
Phone: +45 9940 7519 or 6126 9973